Bile duct stones, also known as choledocholithiasis, are hard deposits that form in the bile ducts, which are tubes that carry bile from the liver and gallbladder to the small intestine. These stones can cause pain, jaundice, and serious complications if not treated promptly. Understanding what causes them can help in prevention and early management.
Causes of Bile Duct Stones
- Gallstones Migration Most bile duct stones form in the gallbladder first and later migrate into the bile duct. Gallstones are made of cholesterol, bile salts, and calcium, and their movement can block the flow of bile.
- Cholesterol Imbalance High cholesterol in bile can lead to crystal formation, eventually turning into stones. Conditions like obesity, high-fat diet, and certain metabolic disorders increase this risk.
- Infections and Inflammation Bile duct infections (cholangitis) or inflammation of the gallbladder (cholecystitis) can contribute to stone formation. Chronic infections can change bile composition and promote stone development.
- Bile Duct Abnormalities Narrowing or strictures in the bile duct, congenital abnormalities, or previous surgeries can disrupt bile flow and encourage stone formation.
- Genetics and Age Family history of gallstones, age above 40, and female gender are common risk factors.
- Other Health Conditions Conditions like liver disease, diabetes, or rapid weight loss can also increase the likelihood of bile duct stones.
Symptoms to Watch For
- Severe upper abdominal pain, often radiating to the back or right shoulder
- Nausea and vomiting
- Yellowing of skin or eyes (jaundice)
- Dark urine or pale stools
- Fever and chills (if infection develops)
Treatment Options
Treatment depends on the size, location, and number of stones:
- Endoscopic Retrograde Cholangiopancreatography (ERCP): A minimally invasive procedure to remove stones from the bile duct.
- Surgery: In some cases, laparoscopic or open surgery may be needed to remove stones.
- Medication: Rarely, bile acid pills may help dissolve cholesterol stones.
Prevention Tips
- Maintain a healthy weight and balanced diet
- Stay hydrated and include fiber-rich foods
- Manage underlying health conditions like diabetes or liver disease
- Regular check-ups if you have a history of gallstones
Dr. Shashank Adgudwar, Surgery 101, emphasizes that early diagnosis and timely treatment of bile duct stones can prevent serious complications like cholangitis or pancreatitis. If you experience persistent abdominal pain or jaundice, consult a specialist immediately.

